Description

Buy Ketamine Powder UK

Buy Ketamine Powder UK Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a treatment for depression and in pain management.^[19] Ketamine is an NMDA receptor antagonist which accounts for most of its psychoactive effects.^[20]

At anesthetic doses, ketamine induces a state of dissociative anesthesia, a trance-like state providing pain relief, sedation, and amnesia.^[21] Its distinguishing features as an anesthestic are preserved breathing and airway reflexes, stimulated heart function with increased blood pressure, and moderate bronchodilation.^[21] At lower, sub-anesthetic doses, it is a promising agent for treatment of pain and treatment-resistant depression.^[22] As with many antidepressants, the results of a single administration wane with time.^[23]

Buy Ketamine Powder UK

Ketamine is used as a recreational drug for its hallucinogenic and dissociative effects.^[24] When used recreationally, it is found both in crystalline powder and liquid form, and is often referred to by users as “Special K” or simply “K”. The long-term effects of repeated use are largely unknown and are an area of active investigation.^[25][26][27] Liver and urinary toxicity have been reported among regular users of high doses of ketamine for recreational purposes.^[28]

Ketamine was first synthesized in 1962, derived from phencyclidine in pursuit of a safer anesthetic with fewer hallucinogenic effects.^[29][30] It was approved for use in the United States in 1970.^[19] It has been regularly used in veterinary medicine and was extensively used for surgical anesthesia in the Vietnam War.^[31] It is on the World Health Organization’s List of Essential Medicines.^[32] It is available as a generic medication.^[33]

Ketamine is frequently used in severely injured people and appears to be safe in this group.^[41] It has been widely used for emergency surgery in field conditions in war zones,^[42] for example, during the Vietnam War.^[43] A 2011 clinical practice guideline supports the use of ketamine as a sedative in emergency medicine, including during physically painful procedures.^[21] It is the drug of choice for people in traumatic shock who are at risk of hypotension.^[44] Ketamine is unlikely to lower blood pressure, which is dangerous for people with severe head injury;^[45] in fact, it can raise blood pressure, often making it useful in treating such injuries.^[46][47]

Ketamine is an option in children as the sole anesthetic for minor procedures or as an induction agent followed by neuromuscular blocker and tracheal intubation.^[42] In particular, children with cyanotic heart disease and neuromuscular disorders are good candidates for ketamine anesthesia.^[40][48]